Massachusetts Congressman Edward Markey, the first candidate to jump into the race for the Senate seat that will become vacant when, as expected, John Kerry is confirmed as Secretary of State, has twice passed on chances to make a bid for the upper chamber.
The 66-year-old Democrat has served in the House since 1976. He sat out the 2010 special election to choose a successor to the late Edward Kennedy. The eventual Democratic nominee, Massachusetts Attorney General Martha Coakley, then proceeded to lose in an upset to Republican Scott Brown, depriving Democrats of the 60th vote they needed to overcome Republican filibusters.
In 1984, after nearly eight years in the House, Markey also had an opportunity to run for an open seat when Democrat Paul Tsongas retired. He declined to go for it. The Democratic nominee and eventual victor? John Kerry.